SSRI-induced hyponatremia

A case of SSRI-induced hyponatremia.

Hyponatremia complicates 1% of hospital admissions and can be associated with serious central nervous system effects. We report a case of a 38year-old woman with hyponatremia resulting in seizures and coma. Medications are one of many causes of hyponatremia. This case emphasizes the need to consider selective serotonin reuptake inhibitors (SSRIs) as a potential source of hyponatremia in all age...

Running Head: SSRI-INDUCED SEXUAL DYSFUNTION 1 Assessing, Diagnosing, and Treating SSRI-Induced Sexual Dysfunction

Thiazide-Induced Hyponatremia

The importance of thiazide-induced hyponatremia (TIH) is reemerging because thiazide diuretic prescription seems to be increasing after the guidelines recommending thiazides as first-line treatment of essential hypertension have been introduced. Thiazide diuretics act by inhibiting reabsorption of Na(+) and Cl(-) from the distal convoluted tubule by blocking the thiazide-sensitive Na(+)/Cl(-) c...

Terlipressin Induced Severe Hyponatremia.

Terlipressin is a vasopressin analogue used for its vasoconstrictor effect in the treatment of variceal bleeding. Despite its good safety profile compared to vasopressin, some adverse reactions may occur during its use - e.g. hyponatremia. We describe a case of a cirrhotic patient with active variceal bleeding treated during two separate hospitalizations with terlipressin. In both drug treatmen...

Hyponatremia-Induced Osteoporosis

There is a high prevalence of chronic hyponatremia in the elderly, frequently owing to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). Recent reports have shown that even mild hyponatremia is associated with impaired gait stability and increased falls. An increased risk of falls among elderly hyponatremic patients represents a risk factor for fractures, which would be furt...